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In the Ugandan RCT the rate of moderate adverse events was 3% and severe 0.2% [Gray et al., 2007a], i.e., 1 event per 500 surgeries.The severe events included 1 wound infection, 2 hematomas that required re-exploration and ligation of bleeding vessels, one wound disruption due to an external cause, and one postoperative herpetic ulceration [Gray et al., 2007a].When the sex of an organism is determined by the sex chromosomes, males and females are generally produced in equal numbers.In other organisms, such as bees and wasps, in which females develop from fertilized eggs and males develop from unfertilized eggs, distribution of the sexes is unequal.Clinging to rocks and to each other, they form piles. If another limpet attaches itself on top of the male limpet, the newcomer becomes male, and the male limpet beneath it reverts to being female.These slipper limpets show the evolutionarily advanced feature of internal fertilization, and the male on top extends his reproductive organ down the pile of females below him to fertilize their eggs.Thanks to high school biology, we are accustomed to thinking of the sex of an organism as being determined by the chromosomes, notably the sex chromosome in humans (designated X or Y).But this is not the whole story, and it applies universally only to mammals and birds.

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If they are incubated below 30 degrees Celsius (86° F), they become females.

The midrange of temperatures results in both male and female offspring.

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